glucose synthesis

By Targets:	DNA/RNA Synthesis (1) AMPK (1) Apoptosis (1) Arp2/3 Complex (1) Biochemical Assay Reagents (2) Drug-Linker Conjugates for ADC (1) Endogenous Metabolite (4) Fatty Acid Synthase (FASN) (1) HDAC (1) Isotope-Labeled Compounds (1) NOD-like Receptor (NLR) (2) PEPCK (1) PKC (1) PROTAC Linkers (5)
By Research Areas:	Cancer (8) Cardiovascular Disease (6) Inflammation/Immunology (3) Metabolic Disease (8) Neurological Disease (1)
Click Chemistry:	PROTAC Synthesis (1) Azide (2) Alkynes (3)

Targets Recommended: DNA/RNA Synthesis GLUT SGLT

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128923

SKF-34288 hydrochloride 1 Publications Verification 3-Mercaptopicolinic acid hydrochloride; 3-MPA hydrochloride	PEPCK	Metabolic Disease
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (K_i: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides .

HY-B0389A

D-Glucose-13C6 3 Publications Verification glucose-¹³C₆; D-(+)-glucose-¹³C₆; Dextrose-¹³C₆	Endogenous Metabolite	Others Metabolic Disease
D-Glucose- ¹³C₆ is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- ¹³C₆ can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .

HY-N2486

Desoxyrhaponticin 1 Publications Verification	Fatty Acid Synthase (FASN) Apoptosis	Cancer
Desoxyrhaponticin is a kind of oral drug that inhibits effective fatty acid synthesis (FASN), and has a fatal effect on cancer cells. Desoxyrhaponticin has the ability to inhibit glucose uptake, improve oral glucose tolerance as a diabetic agent, and possess anti-diabetic effects.

HY-141131

Propargyl-PEG2-beta-D-glucose

PROTAC Linkers Cancer

Propargyl-PEG2-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
HY-141132

Propargyl-PEG4-beta-D-glucose

PROTAC Linkers Cancer

Propargyl-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Propargyl-PEG2-beta-D-glucose	PROTAC Linkers	Cancer
Propargyl-PEG2-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Propargyl-PEG4-beta-D-glucose	PROTAC Linkers	Cancer
Propargyl-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-128747

α-D-Glucose-1-phosphate disodium	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
α-D-Glucose-1-phosphate disodium is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element .

HY-128747A

α-D-Glucose-1-phosphate disodium hydrate	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
α-D-Glucose-1-phosphate disodium hydrate is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium hydrate can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element .

HY-141133

Propargyl-PEG4-tetra-Ac-beta-D-glucose

PROTAC Linkers Cancer

Propargyl-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
HY-141127

Azido-PEG4-tetra-Ac-beta-D-glucose

PROTAC Linkers Cancer

Azido-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Propargyl-PEG4-tetra-Ac-beta-D-glucose	PROTAC Linkers	Cancer
Propargyl-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Azido-PEG4-tetra-Ac-beta-D-glucose	PROTAC Linkers	Cancer
Azido-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-N9535

tert-OMe-byakangelicin	Others	Metabolic Disease
tert-OMe-byakangelicin is a coumarin that can enhances the adrenaline-induced lipolytic effect and inhibits insulin-stimulated triglyceride synthesis from glucose in fat cells .

HY-19997

Mannose triflate TATM	Biochemical Assay Reagents	Others Cancer
Mannose triflate is a glucose analog. Mannose triflate is a well-known precursor for 18F-FDG synthesis for PET applications. 18F-FDG is an imaging technique of cancer .

HY-W011082

NLRP3-IN-2	NOD-like Receptor (NLR)	Cardiovascular Disease
NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism .

HY-160247

Boc-Lys-PEG8-N-bis(D-glucose)	Drug-Linker Conjugates for ADC	Others
Boc-Lys-PEG8-N-bis(D-glucose) (compound 89-5) is a drug linker that can be used in the synthesis of antibody-drug conjugates (ADCs) extracted from patent WO2023280227A2 .

HY-140012

Azido-PEG4-beta-D-glucose	PROTAC Linkers	Cancer
Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-beta-D-glucose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-N7676

Marein	AMPK HDAC	Cardiovascular Disease Neurological Disease Metabolic Disease
Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC₅₀ of 100 µM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects .

HY-N6701

Dihydrocytochalasin B	Arp2/3 Complex	Cancer
Dihydrocytochalasin B (H2CB) is a Cytokinesis inhibitor and changes the morphology of the cells, similar to that of cytochalasin B; does not inhibit glucose transport . Dihydrocytochalasin B (H2CB) disrupts the actin structure and inhibits the ability of growth factors to stimulate DNA synthesis, reversibly blocks initiation of DNA synthesis . Dihydrocytochalasin B (H2CB) inhibits active calcium transport and causes a Ca ²⁺increase in the mucosal scrapings .

HY-W015912

2-Acetylfuran 2-Furyl methyl ketone	Others	Others
2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran also can be formed from glucose and glycine by Maillard reaction. 2-Acetylfuran can be used to synthesis Cefuroxime .

HY-124418

SBI-477	Others	Metabolic Disease
SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain–containing 4 (ARRDC4). SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes .

HY-W011082R

NLRP3-IN-2 (Standard)	NOD-like Receptor (NLR)	Cardiovascular Disease
NLRP3-IN-2 (Standard) is the analytical standard of NLRP3-IN-2. This product is intended for research and analytical applications. NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism .

HY-108600

CGP-53353 DAPH-7	PKC DNA/RNA Synthesis	Cardiovascular Disease Metabolic Disease
CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC₅₀s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients .

HY-W142618

D-Glucal	Biochemical Assay Reagents	Others
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

HY-N6692S

Diacetoxyscirpenol-13C19	Endogenous Metabolite Isotope-Labeled Compounds	Inflammation/Immunology
Diacetoxyscirpenol- ¹³C19 is ¹³C labeled 2-Acetylfuran (HY-W015912). 2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran also can be formed from glucose and glycine by Maillard reaction. 2-Acetylfuran can be used to synthesis Cefuroxime .

Cat. No.	Product Name	Type

HY-19997

Mannose triflate TATM	Carbohydrates
Mannose triflate is a glucose analog. Mannose triflate is a well-known precursor for 18F-FDG synthesis for PET applications. 18F-FDG is an imaging technique of cancer .

HY-W142618

D-Glucal	Biochemical Assay Reagents
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

D-Glucal

Biochemical Assay Reagents

D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

HY-E70070

Endo-β-N-acetylglucosaminidase (Endo A)	Biochemical Assay Reagents
Endo-β-N-acetylglucosaminidase (Endo A) is an Endo-β-N-acetylglucosaminidases (ENGases) from Arthrobacter protophormiae. Endo-β-N-acetylglucosaminidase (Endo A) can transfer a high-mannose type oligosaccharide to monosaccharides such as N-acetylglucosamine (GlcNAc) and glucose to form a new oligosaccharide. Endo-β-N-acetylglucosaminidase (Endo A) catalyzes glycopeptide synthesis by using Man3GlcNAc-oxazoline .

Endo-β-N-acetylglucosaminidase (Endo A)

Biochemical Assay Reagents

Endo-β-N-acetylglucosaminidase (Endo A) is an Endo-β-N-acetylglucosaminidases (ENGases) from Arthrobacter protophormiae. Endo-β-N-acetylglucosaminidase (Endo A) can transfer a high-mannose type oligosaccharide to monosaccharides such as N-acetylglucosamine (GlcNAc) and glucose to form a new oligosaccharide. Endo-β-N-acetylglucosaminidase (Endo A) catalyzes glycopeptide synthesis by using Man3GlcNAc-oxazoline .

Cat. No.	Product Name

HY-K1046

L-Glutamine (100×), Sterile
L-glutamine is an important amino acid supplement commonly added to mammalian cell culture media. L-glutamine serves as an auxiliary energy source, especially when cells are rapidly dividing. L-glutamine is also important in the production of purine and pyrimidine nucleotides, amino sugars, glutathione, L-glutamate, other amino acids, and plays a role in protein synthesis and glucose production.

L-Glutamine (100×), Sterile

L-glutamine is an important amino acid supplement commonly added to mammalian cell culture media. L-glutamine serves as an auxiliary energy source, especially when cells are rapidly dividing. L-glutamine is also important in the production of purine and pyrimidine nucleotides, amino sugars, glutathione, L-glutamate, other amino acids, and plays a role in protein synthesis and glucose production.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2486

Desoxyrhaponticin 1 Publications Verification	Structural Classification Monophenols Stilbenes Classification of Application Fields Polygonaceae Source classification Rheum rhabarbarum Linnaeus Phenols Plants Disease Research Fields Rheum tanguticum Cancer	Fatty Acid Synthase (FASN) Apoptosis
Desoxyrhaponticin is a kind of oral drug that inhibits effective fatty acid synthesis (FASN), and has a fatal effect on cancer cells. Desoxyrhaponticin has the ability to inhibit glucose uptake, improve oral glucose tolerance as a diabetic agent, and possess anti-diabetic effects.

HY-128747

α-D-Glucose-1-phosphate disodium	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides Monosaccharides	Endogenous Metabolite
α-D-Glucose-1-phosphate disodium is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element .

HY-128747A

α-D-Glucose-1-phosphate disodium hydrate	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides Monosaccharides	Endogenous Metabolite
α-D-Glucose-1-phosphate disodium hydrate is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium hydrate can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element .

HY-N7676

Marein	Cardiovascular Disease Flavonoids Chalcones other families Classification of Application Fields Neurological Disease Source classification Phenols Polyphenols Plants Disease Research Fields	AMPK HDAC
Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC₅₀ of 100 µM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects .

HY-N9535

tert-OMe-byakangelicin	Classification of Application Fields Source classification Coumarins Metabolic Disease Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields	Others
tert-OMe-byakangelicin is a coumarin that can enhances the adrenaline-induced lipolytic effect and inhibits insulin-stimulated triglyceride synthesis from glucose in fat cells .

Cat. No.	Product Name	Chemical Structure

HY-B0389A

D-Glucose-13C6 3 Publications Verification
D-Glucose- ¹³C₆ is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- ¹³C₆ can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .

HY-N6692S

Diacetoxyscirpenol-13C19
Diacetoxyscirpenol- ¹³C19 is ¹³C labeled 2-Acetylfuran (HY-W015912). 2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran also can be formed from glucose and glycine by Maillard reaction. 2-Acetylfuran can be used to synthesis Cefuroxime .

Cat. No.	Product Name		Classification

HY-141131

Propargyl-PEG2-beta-D-glucose

Alkynes

Propargyl-PEG2-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
HY-141132

Propargyl-PEG4-beta-D-glucose

Alkynes

Propargyl-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
HY-141133

Propargyl-PEG4-tetra-Ac-beta-D-glucose

Alkynes

Propargyl-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
HY-141127

Azido-PEG4-tetra-Ac-beta-D-glucose

Azide

Azido-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Propargyl-PEG2-beta-D-glucose		Alkynes
Propargyl-PEG2-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Propargyl-PEG4-beta-D-glucose		Alkynes
Propargyl-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Propargyl-PEG4-tetra-Ac-beta-D-glucose		Alkynes
Propargyl-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Azido-PEG4-tetra-Ac-beta-D-glucose		Azide
Azido-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140012

Azido-PEG4-beta-D-glucose		Azide PROTAC Synthesis
Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-beta-D-glucose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

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Biochemical Assay Reagents

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

glucose synthesis

Inhibitors & Agonists

Biochemical Assay Reagents

MCE Kits

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
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